- Natural selection and evolution of antibiotic resistance in bacteria [online article]
- The "Evolution" of Antibiotic Resistance [online article]
- Compensatory Mutations, Antibiotic Resistance and the Population Genetics of Adaptive Evolution in Bacteria [journal article from Genetics]
Tuesday, March 16, 2010
Anti-Biotic Resistant Bacteria
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ReplyDeleteSorry for the mistake Steph! I've pasted your comment below:
ReplyDeleteThe second article seems to suggest that the transfer of genes from one bacteria to another (horizontal gene transfer) can explain all the genetic diversity (including antibiotic resistance). Here's a lovely experiment detailing how E. coli evolved a completely novel trait, the ability to metabolize citrate, in a single population after 33,000 generations of mutations. The inability of E. coli to metabolize citrate is an identifying characteristic of the species, so this is a really neat example of a major evolutionary change. :)
http://www.pnas.org/content/105/23/7899.full